November 30, 2022 4 min read

Taking CBD Oil for Anxiety: How does it work?

Have you ever been in a scenario where you felt that if you had just a little more confidence in yourself, or you felt just a little bit more focused, you would have done a little bit better? Maybe you would have even produced a drastically different result?

Feeling anxious and distant from your best self can impact your day at work, a career-defining job interview, an important test, your fitness routine, and virtually every other area of your life. Harris Polls surveyed 2,000 Americans about their CBD use. 50% of those who use CBD claimed to do so to relieve their anxiety and stress. Jennifer Aniston even told Us Magazine, “CBD helps with pain, stress, and anxiety. It has all the benefits of marijuana without the high.”

Using CBD oil for anxiety is not FDA-approved, however many doctors are beginning to share the potential benefits of trying CBD for anxiety with their patients. It can be implemented in a variety of ways. Like Jennifer Aniston said, it has all the benefits of marijuana without the high. Industrial hemp was legalized in 2018 with the Trump Administration’s passing of the 2018 Farm Bill and has exploded in popularity since then. The CBD industry is expected to be valued at $9.3 billion in 2020 according to Grand View Research.

cbd for anxiety

What do the clinical studies on CBD show?

Pre-clinical evidence strongly supports CBD as a potential treatment for anxiety. While more research is needed, this study published in 2015 reads, “We found that existing preclinical evidence strongly supports CBD as a treatment for generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder when administered acutely; however, few studies have investigated chronic CBD dosing. 

Another study explored how CBD can affect both sleep and anxiety. The study followed 103 adults total, with 72 of those adults using CBD to combat their anxiety. The research found that anxiety decreased in 57 patients or 79.2% of them within the first month and remained decreased during the rest of the study.

A different study published in 2019 explored the use of CBD on mice with Fragile X Syndrome, a genetic condition that causes intellectual disability. One of the symptoms of this disorder is heightened anxiety and hyperactive behavior. The male mice received either five or 20 milligrams of CBD and it was found that the mice displayed fewer anxiety-related behaviors in all areas of the test. The research noted that the effects of CBD were subtle and did not impair locomotion. The cognitive levels of the mice also remained un-influenced by the administered CBD. This research has led many to the conclusion that taking CBD oil for anxiety might be an alternative to common anxiety medications or treatments. It is important to speak with a CBD-educated physician that knows your medical history before making any changes in your medication or health routine.

Aside from studies using animal models, this double-blind study looked at 37 Japanese teenagers with social anxiety disorder that were between the ages of 18 and 19 years old. The teenagers were either given a placebo or 300 mg of CBD oil. The research showed CBD to decrease anxiety based on both the Fear of Negative Evaluation Questionnaire and the Liebowitz Social Anxiety Scale, and concluded that CBD oil for anxiety could be a useful option in people with social anxiety disorder. The study considered it comparable to Paroxetine, a commonly prescribed anxiety medication. Taking CBD oil for anxiety might have the potential to be an alternative to this medication, which is known to cause side effects. 

How does the human body respond to CBD?


The reason that CBD oil for anxiety is being talked about is because of the endocannabinoid system. This is a system in every human being’s body, and in fact, it is in every other animal’s body that has been studied by scientists. While this system isn’t widely talked about, it is widely-studied. The endocannabinoid system contains receptors, and these receptors are located all throughout our bodies. In our brains, other vital organs, digestive tract, nervous system, there are even endocannabinoid receptors in our skin. CBD is able to help so many different issues because of the widespread body locations of our receptors.

There are two main kinds of receptors, the CB1 and CB2 receptors. Endocannabinoid receptors are designed to receive a compound called cannabinoids, both phytocannabinoids and endocannabinoids. The cannabinoids and the receptors work together to bring the body to a place of balance. Phytocannabinoids are those that exist in plants, and most commonly the cannabis plant. CBD is a phytocannabinoid, THC, CBG, CBN, are all phytocannabinoids. Endocannabinoids are naturally-occuring in the human body, but they work with these receptors in the same way. So, when someone tries CBD oil for anxiety, the CBD is entering the body and meeting these receptors to create a calming and potentially anxiety-reducing effect.

Implementing CBD into your wellness routine is not limited to just taking an oil. BotanCBD’s extended release nanoemulsion CBD softgels are an easy way to receive the benefits of CBD all day long and contain 25 milligrams of CBD per softgel. This product is designed to achieve maximum absorbency, efficacy, and bioavailability through its manufacturing process.